188 Patient-reported outcome measures for health-related quality of life in acne vulgaris: A systematic review of measure development and measurement properties

While multiple patient-reported outcome measures (PROMs) for health-related quality of life exist patients with acne vulgaris, little is known about the validity development and measurement properties these PROMs. A systematic review was conducted following Consensus-based Standards selection health Measurement Instruments (COSMIN) framework. Data were extracted on PROM (target population, domains measured, recall period, language, number items), COSMIN-based pilot study grading, content score (relevance, comprehensiveness, comprehensibility, overall), (structural validity, internal consistency, reliability, construct responsiveness, error, responsiveness). Quality evidence assigned each measure an overall recommendation rating based property scoring quality. We identified 47 relevant validation or studies pertaining to 10 acne-specific PROMs, 6 Dermatology-specific generic Acne-Q CompAQ received “A” recommendations, remaining acne-specific, dermatology-specific, general HRQoL PROM’s “B” recommendations. The found be validated a sufficient standard support measuring acne-associated life. AcneQoL ASIS could also considered if additional evaluation performed. However, important have not been studied, studied insufficiently all Further research needed better define properties, interpretability PROMs in acne.